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目的观察三草尿毒灵颗粒对腺嘌呤致慢性肾衰大鼠治疗作用。方法将大鼠灌胃腺嘌呤导致慢性肾衰大鼠,分别在给药第9天、18天、27天采血,测其血清Crea、BUN等指标。结果三草尿毒灵颗粒能明显降低腺嘌呤导致肾衰大鼠血清Crea、BUN值,此外,显著提高腺嘌呤导致肾衰大鼠血清TP值,增加腺嘌呤导致肾衰大鼠血清Ca2+值和降低肾脏系数。结论三草尿毒灵颗粒对腺嘌呤致大鼠慢性肾衰竭有一定的治疗作用。
Objective To observe the therapeutic effect of Sancao Niguiling Granules on rats with chronic renal failure induced by adenine. Methods Rat was given adenine for chronic renal failure. Blood samples were collected on the 9th, 18th and 27th day after administration. The serum Crea and BUN levels were measured. Results Sancao Yudanling Granule could significantly reduce serum Crea and BUN in rats with renal failure induced by adenine. In addition, the TP value of serum in rats with renal failure was significantly increased, and the serum Ca2 + value of the rats with renal failure increased Kidney coefficient. Conclusion Sancao Niguiling Granule has a certain therapeutic effect on adenine-induced chronic renal failure in rats.