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原发性甲状腺功能减退(甲减)病人的蝶鞍可以增大,并可并发高催乳素(PRL)血症,其原因不明。本文报告19例甲减并发高催乳素血症及垂体异常的情况,以及甲状腺素(T_4)替代治疗28个月后的变化。本组连续接诊的甲减19例,治疗前(T_4)为21.4±16(正常58～174)nmol/L,促甲状腺素(TSH)均升高,其中15例高于50(正常0.4～5)mU/L。初诊时 PRL 水平正常者7例(其中TSH>50mU/L者4例),升高者12例(45.4～2612mU/L)。
Primary hypothyroidism (hypothyroidism) in patients with sella can be increased, and may be complicated by hyperprolactinemia (PRL) blood for unknown reasons. This article reports 19 cases of hypothyroidism complicated by hyperprolactinemia and pituitary abnormalities, and thyroid hormone (T_4) replacement therapy after 28 months of change. In our group, 19 cases were given hypothyroidism consecutively, the T_4 was 21.4 ± 16 (normal 58 ~ 174) nmol / L and the thyroid stimulating hormone (TSH) were increased, of which 15 were higher than 50 (normal 0.4 ~ 5) mU / L. In the first visit, PRL was normal in 7 cases (including TSH> 50mU / L in 4 cases), elevated in 12 cases (45.4 ~ 2612mU / L).