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铅是常见的工业毒物,研究铅引起的细胞遗传学效应,对探讨铅的毒理,保护铅作业工人及其后代的健康都有一定的价值。本文就国内外在这方面的研究作一综述。一、铅对体细胞染色体的影响 1.体外细胞培养 Banchinger等用浓度10~(-4)～10~(-3)M的醋酸铅处理体外培养的中国仓鼠细胞,发现分裂指数下降以及染色体裂隙增多。Beek等也发现用
Lead is a common industrial poison. Studying the cytogenetic effects caused by lead has certain value in exploring lead toxicity and protecting the health of lead workers and their offspring. This article reviews the research in this field at home and abroad. I. Effect of Lead on Somatic Chromosomes 1. In vitro Cell Culture Banchinger et al. Treated Chinese hamster cells cultured in vitro with 10 ~ (-4) ~ 10 ~ (-3) M lead acetate and found that the mitotic index decreased and the number of chromosome fissures increased . Beek also found that use