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目的:分析杭州市戊型病毒性肝炎发病及人群感染情况。方法:根据法定传染病系统分析杭州市2004-2011年戊肝疫情资料;采用整群随机抽样方法,抽取拱墅区和桐庐县的健康人群1 483人,应用ELSA法检测戊肝抗体。结果:2004年至2011年,共报告戊肝病例3 490例,发病率(4.19~8.10)/10万,死亡3例,年发病率逐年上升,疫情以散发病例为主。发病年龄以30岁以上年龄组为主,男女平均发病率性别比为2.35∶1,职业以农民较多,春季是流行季节。血清流行病学调查显示,全市人群标化感染率为36.87%,50岁组感染率最高,农村人群感染高于城市人群,男女性别之间感染率无差异。结论:戊肝发病呈逐年上升趋势,应加强戊肝的监测与防治工作。
Objective: To analyze the incidence and population infection of hepatitis E in Hangzhou. Methods: According to the statutory infectious disease system, the epidemic situation of hepatitis E in Hangzhou during 2004-2011 was analyzed. A total of 1 483 healthy people in Gongshu District and Tonglu County were sampled by cluster random sampling method. The antibody against hepatitis E was detected by ELISA. Results: From 2004 to 2011, a total of 3490 cases of hepatitis E were reported. The incidence rate was 4.19 ~ 8.10 per 100,000. There were 3 deaths. The annual incidence rate increased year by year. The epidemic situation mainly consisted of sporadic cases. The age of onset is dominated by the age group of over 30, with an average sex ratio of 2.35: 1 for males and females. More peasants are employed in occupations and spring is the popular season. Serological epidemiological survey showed that the city’s population standardized infection rate was 36.87%, 50-year-old group the highest infection rate, rural population infection is higher than the urban population, no difference in infection rates between men and women. Conclusion: The incidence of hepatitis E is increasing year by year. The monitoring and prevention of hepatitis E should be strengthened.