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对50名无明显阻力性难产,而因子宫收缩乏力引起产程延缓,用催产素进行治疗初产妇所用的催产素滴度、子宫收缩力水平变化及血和羊水中雌、孕激素水平之间关系进行分析。结果表明:(1)应用催产素前的子宫收缩力分别为334±188KPaS/15min,或89±52MU/15min;应用催产素后分别为1201±241KPaS/15min,或308±68MU/15min,后者明显高于前者,有显著性差异(P<0.001)。(2)有效催产素滴度范围是:2—6mU/min,但74％≤10mU/min。(3)产力难产组羊水中雌二醇水平与催产素滴度间相关系数γ=-0.4120,P<0.05。此结果提示子宫对催产素的敏感性与羊水中雌激素水平有关。
50 no obvious obstructive dystocia, but due to uterine atony induced delayed labor, oxytocin used for treatment of primipara by oxytocin titers, changes in uterine contractility and blood and amniotic fluid in the relationship between the level of estrogen and progesterone Analyze. The results showed that: (1) Uterine contractility before application of oxytocin was 334 ± 188KPaS / 15min, or 89 ± 52MU / 15min, respectively; 1201 ± 241KPaS / 15min or 308 ± 68MU / 15min after oxytocin administration, Significantly higher than the former, there was a significant difference (P <0.001). (2) Effective oxytocin titers ranged from 2-6 mU / min, but 74% ≤10 mU / min. (3) The correlation coefficient γ = -0.4120, P <0.05 between the estradiol level and the oxytocin titers in amniotic fluid of labor dystocia group. This result suggests that the sensitivity of the uterus to oxytocin and amniotic fluid levels of estrogen.