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为提高对纯红细胞再生障碍性贫血 (PRCA)发病机制、诊断和治疗的认识 ,对 37例 PRCA住院患者进行回顾性分析。先天性 5例 ,获得性 32例 ,其中继发性 2 6例 ,因感染所致者占继发性的 6 9.2 %。本组资料证明儿童继发性纯红再障可有白细胞减少或增多及血小板降低 ,骨髓象可有粒系、巨核细胞及淋巴细胞的改变 ,并非是单纯红系造血衰竭。免疫学 2 8例 ,17例有体液和细胞免疫方面的异常。应用激素及免疫抑制剂有效。
To improve understanding of the pathogenesis, diagnosis and treatment of pure red cell aplastic anemia (PRCA), 37 cases of PRCA inpatients were retrospectively analyzed. Congenital in 5 cases, acquired 32 cases, of which 26 cases of secondary, due to infection accounted for 62.9% of secondary. This group of data prove that secondary purpura aplastic anemia in children may have leukopenia or increased thrombocytopenia, bone marrow may have granulocytes, megakaryocytes and lymphocyte changes, not simply erythroid hematopoietic failure. 28 cases of immunology, 17 cases of humoral and cellular immune abnormalities. Application of hormones and immunosuppressive agents effective.