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目的:探讨在悬雍垂腭咽成形术(UPPP)后应用地塞米松能否明显降低并发症的发病率。方法:治疗组30例患者UPPP术后静脉应用地塞米松3 d,对照组30例患者UPPP术后不使用地塞米松,其余治疗相同,比较两组之间并发症的差异。结果:术后1 d, 治疗组和对照组在呼吸困难,咽部水肿,咽部疼痛,切口裂开,术后出血及发热方面均有显著差异(P<0.05)。术后3 d,治疗组和对照组在咽部水肿,咽部疼痛,切口裂开,术后出血及发热方面均有显著差异(P<0.05),在呼吸困难方面无显著差异。术后1周,治疗组和对照组在咽部水肿,咽部疼痛,切口裂开,术后出血方面均有显著差异(P<0.05),在呼吸困难、发热方面无显著差异。结论:在悬雍垂腭咽成形术(UPPP)后应用地塞米松能明显降低并发症的发病率。
Objective: To investigate whether dexamethasone can significantly reduce the incidence of complications after uvulopalatopharyngoplasty (UPPP). Methods: Thirty patients in the treatment group received intravenous dexamethasone for 3 days after UPPP. Thirty patients in the control group did not receive dexamethasone after UPPP, and the rest of the treatment was the same. Comparisons were made between the two groups. Results: On the first postoperative day, the treatment group and the control group showed significant differences in dyspnea, pharyngeal edema, pharyngeal pain, incision rupture, postoperative bleeding and fever (P <0.05). At 3 days after operation, the treatment group and the control group had significant differences (P <0.05) in pharyngeal edema, pharyngeal pain, incision rupture, postoperative hemorrhage and fever, and no significant difference in dyspnea. One week after operation, the treatment group and the control group showed significant differences (P <0.05) in the pharyngeal edema, pharyngeal pain, incision rupture and postoperative bleeding, and no significant difference in dyspnea and fever. Conclusion: The application of dexamethasone after uvulopalatopharyngoplasty (UPPP) can significantly reduce the incidence of complications.