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目的:探讨替硝唑治疗成人牙周炎的有效性及其安全性。方法:选取2015年期间于我院就诊的64例牙周炎患者为研究对象,平均分为对照组和治疗组,每组各32例。对照组使用甲硝唑进行治疗,治疗组使用替硝唑进行治疗,分析并比较两组患者的治疗疗效和不良反应发生状况。结果:对照组总有效率为65.62%,显著低于治疗组的90.62%;对照组不良反应发生率为15.62%,显著高于治疗组的9.37%。结论:临床应用替硝唑和甲硝唑对于牙周炎患者有着良好的疗效,相比之下替硝唑在改善牙周炎的症状并和控制其病理情况的发展等方面,临床应用价值比甲硝唑高。
Objective: To investigate the effectiveness and safety of tinidazole in the treatment of adult periodontitis. Methods: A total of 64 patients with periodontitis who were treated in our hospital during 2015 were selected as study subjects, equally divided into control group and treatment group, with 32 cases in each group. The control group was treated with metronidazole. The treatment group was treated with tinidazole. The curative effect and adverse reactions of the two groups were analyzed and compared. Results: The total effective rate of the control group was 65.62%, which was significantly lower than that of the treatment group (90.62%). The incidence of adverse reactions in the control group was 15.62%, which was significantly higher than that of the treatment group (9.37%). Conclusion: Clinical application of tinidazole and metronidazole for patients with periodontitis have a good effect, compared with tinidazole in improving the symptoms of periodontitis and control the development of its pathological aspects, the clinical value Metronidazole high.