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目的探讨单心动周期实时三维超声心动图(sRT-3DE)评价左心室收缩功能的可行性及临床价值。方法应用sRT-3DE与多心动周期实时三维超声心动图(mRT-3DE)测量50例健康志愿者(正常组)和27例左心室扩大者(病例组)的左心室舒张末容积(LVEDV)、收缩末容积(LVESV)、每博量(SV)及射血分数(EF),分别比较正常组和病例组sRT-3DE和mRT-3DE左室收缩功能指标的测量值;分析上述两种方法的相关性。结果①所有受试者均获得了满意的实时三维超声图像。正常组及病例组sRT-3DE与mRT-3DE法所测LVEDV、LVESV、SV、EF值差异均无统计学意义(P均>0.05)。②正常组和病例组sRT-3DE及mRT-3DE法测值相关性良好。正常组r分别为0.805、0.658、0.843、0.927(P均<0.05),病例组r分别为0.955、0.873、0.917、0.978(P均<0.05)。③sRT-3DE法观察者内及观察者间测值均具有良好的重复性,变异系数分别为7.27%、8.94%、10.42%、6.51%和7.44%、10.66%、9.39%、7.07%。结论 sRT-3DE图像无拼接伪像,可实时、准确评价左心室收缩功能,尤其适用于左心室扩大者。
Objective To investigate the feasibility and clinical value of single cardiac cycle real-time three-dimensional echocardiography (sRT-3DE) in evaluating left ventricular systolic function. Methods The left ventricular end-diastolic volume (LVEDV) of 50 healthy volunteers (normal group) and 27 patients with left ventricular enlargement (case group) were measured by real-time three-dimensional echocardiography (mRT-3DE) LVESV, SV and EF were measured to compare the measured values of sRT-3DE and mRT-3DE left ventricular systolic function in normal group and case group respectively. Correlation. Results ① All the subjects got satisfactory real-time three-dimensional ultrasound images. There were no significant differences in LVEDV, LVESV, SV and EF between the normal group and the case group by sRT-3DE and mRT-3DE (all P> 0.05). ② normal group and the case group sRT-3DE and mRT-3DE measured good correlation. The normal group r were 0.805,0.658,0.843,0.927 respectively (all P <0.05). The patients in group R were 0.955,0.873,0.917 and 0.978 respectively (all P <0.05). The results of SRT-3DE method showed good repeatability within and between observers, with coefficients of variation of 7.27%, 8.94%, 10.42%, 6.51% and 7.44%, 10.66%, 9.39% and 7.07%, respectively. Conclusion sRT-3DE images without stitching artifacts, real-time, accurate assessment of left ventricular systolic function, especially for patients with left ventricular enlargement.