高原缺氧是高原环境中影响生命活动的主要因素,当急速进入高原地区时,机体会受到不同程度的损伤,而以心肺损伤较显著,其具体损伤程度主要取决于海拔高度和机体对低氧的适应性。以往研究显示,缺氧能引起氧化应激反应,后者具有调节炎性反应、影响肺血管收缩、肺毛细血管通透性及肺泡液体清除等多种生物学作用。高原肺水肿是指由于进入高原速度 Plateau hypoxia is a major factor affecting the life activities in the plateau environment. When entering the plateau rapidly, the body will suffer different degrees of injury, while the cardiopulmonary injury is more significant. The degree of specific damage depends mainly on the altitude and the body’s response to hypoxia Adaptability. Previous studies have shown that hypoxia can cause oxidative stress response, the latter has a variety of biological effects of regulating inflammatory responses, affecting pulmonary vasoconstriction, pulmonary capillary permeability and alveolar fluid clearance. High altitude pulmonary edema is due to enter the plateau speed