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目的探讨心肌速度梯度技术在评价先天性甲状腺功能低下症(CH)患儿左心室舒张功能方面的应用价值。方法应用QTV I技术分析35例甲状腺功能低下症患儿(CH组)及30例正常婴幼儿(对照组)左心室心肌各节段长轴和短轴方向上的速度曲线,测量舒张早期及晚期峰值速度(Ve、Va),并计算长轴和短轴方向上舒张早期及晚期心肌速度梯度MVG1、MVG2和MVG3等参数。结果 CH组患儿左心室后间隔、后壁、前间隔各节段MVG1、MVG2及MV G3较对照组婴幼儿减低明显,差异有统计学意义(P<0.05);CH组患儿左室侧壁、下壁及前壁各节段MVG1、MV G2、MV G3与对照组婴幼儿比较差异无统计学意义(P>0.05)。结论 CH患儿左心室长轴及短轴方向局部心肌舒张功能在一定程度上存在降低,为临床早期干预的依据。
Objective To investigate the value of myocardial velocity gradient in evaluating left ventricular diastolic function in children with congenital hypothyroidism (CH). Methods The QTV I technique was used to analyze the velocity curves of the left and right ventricular myocardium in 35 cases of CHD and 30 normal infants (control group) Peak velocity (Ve, Va), and parameters such as MVG1, MVG2 and MVG3 of early and late diastolic myocardial velocities in long axis and short axis were calculated. Results The MVG1, MVG2 and MV G3 in the posterior septum, the posterior wall and the anterior septum in CH group were significantly lower than those in the control group (P <0.05). In the CH group, the left ventricular The MVG1, MV G2 and MV G3 in the wall, inferior wall and anterior wall were not significantly different from those in the control group (P> 0.05). Conclusion Local diastolic function of left ventricular in the long axis and short axis of left ventricle is reduced to a certain degree, which is the basis of early clinical intervention.