从 Wistar 大鼠的自然群体中筛选出热体、寒体与常体大鼠,作为研究对象。用动物的外周血和脾脏作材料,通过细胞体外培养、紫外线损伤、同位素掺入及液闪测定等方法,观察比较各组大鼠脾淋巴细胞的体外增殖能力,外周淋巴细胞 DNA 损伤后的复制合成能力。结果表明,在此两项实验指标中,热体大鼠比寒体大鼠具有更高的水平,而常体大鼠居中。因而从一个方面证实了《灵枢》所称“其身多热者易已;多寒者,难已”的科学性。 Heat, cold and body rats were selected from the natural population of Wistar rats as a research object. Using animal peripheral blood and spleen as materials, in vitro cell culture, UV damage, isotope incorporation, and liquid scintillation assays were used to observe and compare the in vitro proliferation ability of splenic lymphocytes in each group of rats and the replication of peripheral lymphocytes after DNA damage. Synthesis ability. The results showed that in these two experimental indicators, the hot body rats had higher levels than the cold body rats, while the normal body rats had the middle level. Therefore, from one aspect, it is confirmed that the “Lingshu” is called "the person whose body is hotter than ever;