用胃癌单克隆抗体 MG_7,观察52例老年和老年前期萎缩性胃炎改变的胃粘膜抗原分布情况。其中老年组阳性率48.0％,老年前期组阳性率22.7％,而中青年组和浅表性胃炎组则为阴性。提示:萎缩性胃炎与胃癌发生有密切关系,而老年人胃粘膜萎缩的比例相当大,采用特异性较高的单克隆抗体对老年人萎缩性胃炎筛选,旨在提高老年人胃癌早期诊断。 Using the gastric cancer monoclonal antibody MG_7, the gastric mucosal antigen distribution in 52 cases of atrophic gastritis in the elderly and the elderly was observed. The positive rate in the elderly group was 48.0%, and the positive rate in the pre-senile group was 22.7%, while it was negative in the middle-aged and superficial gastritis groups. Tip: Atrophic gastritis is closely related to the occurrence of gastric cancer, and the proportion of elderly patients with gastric mucosal atrophy is quite large. A specific monoclonal antibody is used to screen atrophic gastritis in the elderly to improve the early diagnosis of gastric cancer in the elderly.