为进一步探讨母乳化早产儿配方奶与发生晚期代谢性酸中毒(LMA)的关系,对我院儿科ICU收治的129例无呼吸、消化、循环系统疾病及感染的早产儿进行了回顾性分析。采用母乳化早产儿配方奶“美素力”“S—26”喂养早产儿,以BE≤-6.0mmol/L或TCO_2≤16mmol/L为诊断标准。结果:129例早产儿中发生LMA 40例,占 31.0％。28例经碳酸氢钠治疗,27例酸中毒纠正,1例死亡。强调即使用母乳化早产儿配方奶喂养早产儿,与母乳喂养相比,仍有较大差距。但在母乳喂养不可能实施的情况下,采用母乳化的早产儿配方奶可比牛奶喂养降低LMA的发病率。 In order to further explore the relationship between formula milk and the occurrence of late metabolic acidosis (LMA) in breast-fed premature infants, a retrospective analysis was performed on 129 non-respiratory, digestive, circulatory and infectious premature infants admitted to pediatric ICU. Preterm infant breastfeeding preterm infant formula “Sulim” “S-26” fed with BE≤-6.0mmol / L or TCO_2≤16mmol / L as the diagnostic criteria. Results: There were 40 LMA cases in 129 preterm infants (31.0%). 28 cases of sodium bicarbonate treatment, 27 cases of acidosis corrected, 1 case died. Emphasizing that the use of formula milk for preterm infant breastfeeding preterm children, compared with breastfeeding, there is still a big gap. However, in the unlikely event that breastfeeding is impracticable, breast milk preterm infant formula may lower the incidence of LMA than milk feed.