论文部分内容阅读
Wick曾报道多巴甲酯(1)对小鼠L_(1210),P_(388)淋巴白血病和B_(16)黑色素瘤有明显抑制作用,并能选择性地抑制B_(16)细胞DNA的合成和黑色素的形成。3,4-二羟基苯乙胺(2)也具有和化合物(1)相似的抗肿瘤作用。
Wick has reported that dopa methyl ester (1) has a significant inhibitory effect on mouse L 1210, P 388 lymphoblastic leukemia and B 16 melanoma and selectively inhibits the DNA synthesis of B 16 cells And the formation of melanin. 3,4-Dihydroxyphenethylamine (2) also has an antitumor effect similar to compound (1).