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大部分并发分泌性中耳炎的鼻咽癌患者的咽鼓管是开放的 ,传统的机械压迫及淋巴回流障碍的学说受到很大挑战。鼻咽腔气流变化、神经 -肌肉麻痹及咽鼓管顺应性改变是导致中耳负压的主要原因。放疗后 6 0个月咽鼓管功能最差 ,可表现为假性感音神经性听力损失。在内耳损伤方面 ,高频听力损失重于言语频率损失。射线对窝后听系统有不可忽视的损害。顺铂的耳毒性由自由基产物引起 ,首先损伤外毛细胞。通过综合防治可使听功能损害减到最低
Most eustachian tubes in patients with nasopharyngeal carcinoma with secretory otitis media are open, and the notion of traditional mechanical compression and lymphatic drainage disorders is greatly challenged. Nasopharyngeal airflow changes, neuromuscular paralysis and eustachian tube compliance changes are the main causes of negative pressure in the middle ear. Eustachian tube function 60 months after radiotherapy worst, can be manifested as pseudo-sensorineural hearing loss. In terms of inner ear damage, high frequency hearing loss is more severe than verbal frequency loss. Radiation on the nest after hearing system can not be ignored damage. Cortico-ototoxicity is caused by free radical products, which first damage outer hair cells. Through comprehensive prevention of hearing loss can be minimized