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目的 :研究新生儿胆红素脑病的临床危险因素,为患儿病症的治疗提供临床依据。方法 :选取医院2013年7月-2014年7月确诊为胆红素脑病的60例新生儿为观察组,并选择同期筛选的60例无胆红素脑病的新生儿为对照组,比较两组新生儿的各种因素,并详细记录病症发生因素。结果:两组新生儿除胎龄和窒息缺氧发生率无显著差异外(p>0.05),其他各项指标和发生率(出生体质量、12小时内出现黄疸、新生儿溶血、低蛋白血症、酸中毒、G-6-PD缺乏症、总胆红素峰值),观察组均显著高于对照组,差异有统计学意义(p<0.05)。结论 :新生儿胆红素脑病的临床危险因素是多方面的,针对这些危险因素,患儿家属和医生需要密切关注,尽可能的给予避免,这样才能降低新生儿胆红素脑病的发生。
Objective: To study the clinical risk factors of neonatal bilirubin encephalopathy and provide a clinical basis for the treatment of the disease in children. Methods: Sixty newborns diagnosed with bilirubin encephalopathy from July 2013 to July 2014 in our hospital were selected as the observation group. Sixty newborn infants without bilirubin encephalopathy were selected as the control group. The two groups were compared Neonatal various factors, and detailed records of the disease factors. Results: Except for gestational age and asphyxia, there was no significant difference in the incidence of neonatal hypoxia between the two groups (p> 0.05). Other indicators and incidence (birth weight, jaundice, hemolysis in neonates, hypoproteinemia Disease, acidosis, G-6-PD deficiency, total bilirubin peak), the observation group were significantly higher than the control group, the difference was statistically significant (p <0.05). Conclusion: There are many clinical risk factors for neonatal bilirubin encephalopathy. To address these risk factors, family members and physicians need to pay close attention to them and avoid them as much as possible in order to reduce neonatal bilirubin encephalopathy.