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根据美国疾病控制中心提出治疗淋病采用普鲁卡因青霉素480万U进行一次性冲击疗法,该方法我国卫生部已采用,并推荐全国试用。治疗淋病的方案中,青霉素是首选药物,血液内药物的浓度比治疗时间长短更为重要。使用时,480万U普鲁卡因青霉素im,qd(分二侧臀肌注),注射前同时顿服丙磺舒(probenecid)1g,血清青霉素水平的高峰可增高2-4倍。其次是氨苄青霉素、羟氨苄青霉素和诺氟沙星(norfloxacin)。如果对青霉素、头孢菌素与丙磺舒过敏的患者可用
According to the US Centers for Disease Control proposed treatment of gonorrhea procaine penicillin 4.8 million U one-time impact therapy, the method has been adopted by the Ministry of Health, and recommended a national trial. In the treatment of gonorrhea program, penicillin is the drug of choice, the blood concentration of the drug is more important than the length of treatment. When used, 4.8 million U of procaine penicillin im, qd (gluteal muscle injection on both sides), before injection, probenecid 1d, the peak of serum penicillin levels can be increased 2-4 times. Followed by ampicillin, amoxicillin and norfloxacin. If the penicillin, cephalosporin and probenecid allergic patients available