目的　研究人骨骼肌柠檬酸提取物 (CAE)中胸腺瘤特异相关抗原成份。方法　采用免疫印迹法检测 33例重症肌无力 (MG)患者 (有瘤 16例及无瘤 17例 ) ,正常人 10名和其它疾病 18例的血清中 CAE抗体。结果　 CAE抗原中 34 KD、5 0 KD、6 0 KD组份与 MG有胸腺瘤 (MGT)患者的血清结合显色率分别为 :93.7% (15 / 16例 )、75 % (12 / 16例 )、75 % (12 / 16例 ) ,而其它组无 1例结合显色。结论　 34 KD、5 0 KD、6 0 KDCAE抗原组份为胸腺瘤特异相关成份 ,可能对 MGT的诊断起一定作用 Objective To study thymoma-specific antigens in human skeletal muscle citrate extract (CAE). Methods Serum CAE antibodies were detected by Western blotting in 33 patients with myasthenia gravis (MG), 16 with and without tumor, 10 with normal controls and 18 with other diseases. Results Serum binding rates of 34 KD, 50 KD, 60 KD and MG thymoma in CAE antigen were 93.7% (15/16), 75% (12/16) ), 75% (12/16 cases), while no other group combined with color. Conclusion The 34 KD, 50 KD and 60 KDCAE antigen components are specific components of thymoma and may play a role in the diagnosis of MGT