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目的探索早期筛查自杀高危人群无伤无害的生化指标。方法对某部2014年入伍第1个月的新兵727人,采用自杀意念自评量表(SIOSS)进行自杀意念普查,以≥12分为划界分,有25人(实际27人,两人因故未参加)入自杀意念组,从无自杀意念的新兵中随机抽取25人作为对照组;分别在进入新兵训练1和3个月后采集唾液进行生化分析,同时采用SIOSS再次进行自杀意念测试。结果新兵训练1个月唾液生化分析显示,自杀意念组与无自杀意念对照组唾液钙、镁、淀粉酶(Amy)、唾液酸(SA)含量存在统计学差异(P<0.05),但各项指标与SIOSS评分无显著直线相关(P>0.05);新兵训练3个月唾液生化分析显示,按首次自杀意念普查分成的自杀意念组与对照组唾液钙、镁、Amy、SA含量已无统计学差异(P>0.05)。结论新兵入伍第1个月,筛查出的自杀意念者唾液生化成分改变,可能与机体应激有关;采用唾液生化指标筛查自杀意念者缺乏生物学特异性。
Objective To explore the biochemical indicators of non-injury and harmless screening of early high risk suicide patients. Methods A total of 727 recruits from the first month in 2014 were enrolled. The suicidal ideation survey was conducted using the SIOSS (suicidal ideation and self-rating scale), with 25 divided by ≥12 (actually 27, two Because they did not participate) into the suicide ideation group, recruits randomly from 25 recruits without suicide ideation as a control group; saliva were collected biochemical analysis after recruits recruits 1 and 3 months, respectively, while using SIOSS again suicide ideation test . Results One month salvage biochemical analysis showed that salivary calcium, magnesium, amylase and sialic acid (SA) contents in suicidal ideation group and suicidal ideation control group were significantly different (P <0.05), but all There was no significant linear correlation between the index and the SIOSS score (P> 0.05). The biochemical analysis of saliva in recruits for 3 months showed that there was no statistical significance in the salivary calcium, magnesium, Amy, SA content of suicidal ideation group and control group according to the first suicidal ideation census Difference (P> 0.05). Conclusion The changes of saliva biochemical components in the first month of enlistment may be related to the stress of the body. There is a lack of biological specificity in using salivary biochemical markers to screen suicidal ideation.