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目的探讨瑞巴派特与硫糖铝治疗慢性非萎缩性胃炎患者消化不良症状的临床效果。方法选择慢性非萎缩性胃炎患者98例,随机分为对照组和观察组,每组49例。对照组应用硫糖铝治疗,观察组患者在对照组的基础上联合瑞巴派特,治疗后比较两组患者消化不良症状缓解情况、炎症治疗效果、临床治疗效果。结果观察组患者呃逆饱胀、反酸、胃灼烧、上腹痛等消化不良症状缓解情况优于对照组;观察组炎症治疗总有效率和消化不良症状缓解率均优于对照组,组间比较差异有统计学意义(P<0.05)。结论瑞巴派特联合硫糖铝可明显改善慢性非萎缩性胃炎患者的消化不良症状,减少患者胃黏膜的炎性反应,提高治疗有效率,值得临床广泛应用。
Objective To investigate the clinical effect of rebamipide and sucralfate in treating dyspeptic symptoms in patients with chronic non-atrophic gastritis. Methods Ninety-eight patients with chronic non-atrophic gastritis were randomly divided into control group and observation group, with 49 cases in each group. The control group was treated with sucralfate. The patients in the observation group were given rebamipide on the basis of the control group. The patients in the two groups were compared for their relief of dyspepsia, inflammation treatment and clinical treatment. Results In the observation group, the edema and swellings were better than those in the control group. The total effective rate of the inflammatory response and the remission rate of dyspeptic symptoms in the observation group were better than those in the control group The difference was statistically significant (P <0.05). Conclusion rebamipide combined with sucralfate can significantly improve the patients with chronic non-atrophic gastritis dyspepsia, reduce the patient’s gastric mucosal inflammatory response and improve the treatment efficiency, it is widely used in clinical.