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对1OO例进展期胃癌临床病理资料及手术标本3种性激素受体HR)检测结果的性别比较,证实男女胄癌在发生率、年龄分布、大体及组织学类型以及癌组织HR状况笑了面存在的显著差异,推测男女胄癌临床病理表现的诸多差异是由于体内各种性激素的浓度不同以及癌组织内相应受体的含量不同造成,部分胃癌可能为性激素依赖性(雌激素依赖性或雄激素依赖性〕,提出对胃癌进行内分泌治疗的可能性。
The gender comparison of the clinicopathological data of 1OO cases of advanced gastric cancer and the three sex hormone receptor HR test results of surgical specimens confirmed the presence of male and female cancer patients in the occurrence rate, age distribution, general and histological types, and cancer tissue HR status. The significant differences suggest that many differences in the clinicopathological features of male and female carcinoid tumors are due to different concentrations of various sex hormones in the body and different levels of corresponding receptors in cancer tissues. Some of the gastric cancers may be sex hormone dependent (estrogen dependence or androgen Dependence] proposes the possibility of endocrine therapy for gastric cancer.