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目的探讨胰岛素联合抗菌药物治疗类风湿关节炎继发糖尿病患者肺部感染的临床效果,为临床治疗提供参考依据。方法选择2007年3月-2012年12月医院收治的80例类风湿关节炎继发糖尿病患者发生肺感染的临床资料,将其分为观察组和对照组,每组各40例,观察组患者采用胰岛素联合抗菌药物进行治疗,对照组患者使用口服降糖药联合抗菌药物进行治疗,比较两组患者的治疗效果,数据采用SPSS 17.0统计软件进行分析。结果观察组患者的血糖达标时间及住院时间分别为(4.3±0.5)d、(8.0±2.1)d,均明显优于对照组患者,且差异有统计学意义(P<0.05),而且观察组患者的总有效率为100.0%,明显高于对照组患者的85.0%,差异有统计学意义(P<0.05)。结论胰岛素联合抗菌药物治疗类风湿关节炎继发糖尿病并发肺感染患者疗效显著,有效缩短住院时间节省费用,值得临床广泛应用。
Objective To investigate the clinical effect of insulin combined with antibiotics in the treatment of pulmonary infection in patients with rheumatoid arthritis secondary to diabetes and provide reference for clinical treatment. Methods Clinical data of 80 cases of pulmonary infection in patients with rheumatoid arthritis secondary diabetes mellitus were selected from March 2007 to December 2012 and divided into observation group and control group, 40 cases in each group. Patients in observation group The patients in the control group were treated with oral hypoglycemic agents and antimicrobial agents. The treatment effect was compared between the two groups. The data were analyzed by SPSS 17.0 statistical software. Results The observed time and length of hospital stay in the observation group were (4.3 ± 0.5) days and (8.0 ± 2.1) days, respectively, which were significantly better than those in the control group (P <0.05) The total effective rate of patients was 100.0%, which was significantly higher than that of the control group (85.0%), the difference was statistically significant (P <0.05). Conclusion The combination of insulin and antimicrobial agents in the treatment of rheumatoid arthritis secondary diabetes mellitus complicated by pulmonary infection has significant curative effect, effectively shortening the hospitalization time saving cost and deserving to be widely used clinically.