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癲癇的药物治疗已經有一百多年的历史。自从1936年报道苯妥英治疗癲癇有效后,为治疗癲癇药物开辟了新的途径。二十多年来,出現了許多新类型的抗癲癇药,在临床上它們可以控制大多数癲癇病人的发作或者使之减輕;但仍然有一部分病人对現有的药物效果不好或者无效,而且,現有的药物在长期服用时往往会出現毒性反应,迫使病人停止治疗或改用它药。所以,进一步寻找和发現新的有效药物仍然是今后的迫切任务。本文拟将临床上常用的抗癲癇药的药理作用和应用扼要介紹,对一些新近出現的药物而临床上确有一定优点和疗效者也有选择地介紹,供同志們参考。
Epilepsy drug treatment has been a hundred years of history. Since 1936 phenytoin treatment of epilepsy reported effective, opened up a new way for the treatment of epilepsy drugs. For more than two decades there have been many new types of antiepileptic drugs that can clinically control the onset or reduce the incidence of most epileptic patients; however, some patients still have poor or ineffective effects on existing medications and , Existing drugs tend to be toxic when used for long periods of time, forcing patients to stop treatment or switch to drugs. Therefore, further searching for and discovering new and effective drugs will remain an urgent task in the future. This article intends to clinically common antiepileptic drugs pharmacological effects and applications brief introduction of some of the newly emerging drugs and clinically there are certain advantages and curative effect are also selectively introduced for comrades for reference.