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对35例风湿性二尖瓣狭窄(MS)并主动脉瓣返流(AR)患者进行了经皮球囊二尖瓣扩张术(PBMV)治疗。二尖瓣口面积由1.02±0.33cm~2增至2.08±0.25cm~2(P<0.01),左房平均压由2.68±1.06kPa(50±8mmHg)降至1.27±0.66kPa(10±6mmHg)(P<0.01)。彩色多普勒血流显像测AR 的峰值血流速度由2.73±0.01m/s 增至2.93±0.63m/s(P<0.05),左室射血分数(LVEF)由50±2%增至52±2%(P<0.01),左室径(LVD)无明显增大(P>0.05)。结果提示:MS 并 AR 病人,凡(1)主动脉逆行造影 AR≤I°;(2)临床以活动性气短、心悸为主要症状,周围血管征阴性。(3)LVD≤50mm,LVEF 在正常范围者,PBMV 近期疗效满意。
Percutaneous balloon mitral valvuloplasty (PBMV) was performed on 35 patients with rheumatic mitral stenosis (MS) and aortic regurgitation (AR). Mitral valve area increased from 1.02 ± 0.33cm 2 to 2.08 ± 0.25cm 2 (P <0.01), and the mean left atrial pressure decreased from 2.68 ± 1.06kPa (50 ± 8mmHg) to 1.27 ± 0.66kPa (10 ± 6mmHg ) (P <0.01). The color Doppler flow imaging AR peak blood flow velocity increased from 2.73 ± 0.01m / s to 2.93 ± 0.63m / s (P <0.05), left ventricular ejection fraction (LVEF) increased from 50 ± 2% To 52 ± 2% (P <0.01), LVD did not increase significantly (P> 0.05). The results suggest that: MS and AR patients, where (1) aortic retrograde AR ≤ I °; (2) clinically active shortness of breath, palpitations as the main symptoms of peripheral vascular symptoms. (3) LVD≤50mm, LVEF within the normal range, PBMV recent satisfactory results.