新生儿细菌感染的症状及体征均不典型,不易识别,细菌学及其非特异性检查需要一定时间,为防止病情恶化、不延误最佳治疗时机以避免严重并发症的发生,新生儿期细菌感染常需接受抗菌药物的经验性治疗。新生儿抗菌药物经验性用药在临床有重要地位,可及时有效地控制感染的发展,减少抗菌药物应用时间和医疗资源的使用等。据Baltimore RS等[1]报道,在1996-1999年,对 Neonatal bacterial infection of the symptoms and signs are not typical, not easy to identify, bacteriological and nonspecific examination takes some time, in order to prevent the deterioration of the disease, do not delay the best treatment opportunity to avoid serious complications, neonatal bacterial infection Often need to accept the empirical treatment of antibiotics. Neonatal antimicrobial experience in the clinical medication has an important place, timely and effective control of the development of infection, reducing the application of antibacterial time and the use of medical resources. According to Baltimore RS et al. [1] reported in 1996-1999, yes