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目的观察参麦注射液辅助治疗老年心力衰竭的临床疗效。方法选择老年心力衰竭患者101例,随机分为对照组50例和治疗组51例,两组同样给予吸氧、洋地黄制剂、利尿剂、血管扩张剂、血管紧张素转换酶抑制剂、β受体阻滞剂等常规治疗,治疗组在常规治疗基础上加用参麦注射液。结果治疗组心功能改善总有效率为90.2%,显著高于对照组的60.0%(P<0.01)。治疗组治疗后心率、左室射血分数、每搏量、每分钟心排血量、血浆脑钠肽水平均较治疗前显著改善(均P<0.01);与对照组比较,差异均有统计学意义(均P<0.05)。结论参麦注射液能明显辅助改善老年心力衰竭患者心功能,是一种安全、有效的方法。
Objective To observe the clinical efficacy of Shenmai injection in the treatment of elderly patients with heart failure. Methods 101 elderly patients with heart failure were randomly divided into control group (n = 50) and treatment group (n = 51). The two groups were also given oxygen, digitalis, diuretics, vasodilators, angiotensin converting enzyme inhibitors, Body blockers and other conventional treatment, the treatment group on the basis of conventional treatment with Shenmai injection. Results The total effective rate of improvement of cardiac function in the treatment group was 90.2%, which was significantly higher than that in the control group (60.0%, P <0.01). After treatment, heart rate, left ventricular ejection fraction, stroke volume, cardiac output per minute and plasma brain natriuretic peptide in treatment group were significantly improved (all P <0.01) compared with those in control group Significance (both P <0.05). Conclusion Shenmai injection can significantly improve heart function in elderly patients with heart failure, is a safe and effective method.