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目的了解住院患者人群中梅毒抗体的阳性率及分布情况,为预防和治疗梅毒提供科学依据。方法对被检者的标本用ELISA初筛,阳性者再用TPPA确诊。结果在59 282份血清标本中,经TPPA检测阳性1 834例,阳性率3.09%;其中男性865例,女性969例,不同性别患者梅毒血清学阳性比较,差异无统计学意义;>60岁组感染率最高,为5.39%,与其他组比较,差异有统计学意义(χ2=257.42,Р<0.01);不同年份住院患者梅毒血清阳性率不同,从2008年-2013年住院患者梅毒血清阳性率呈逐年递减趋势;梅毒血清学阳性患者在各科室分布不均衡,分布于各个临床科室,内科系统高居首位,感染率为4.41%,其次为普外科,感染率为3.62%。结论目前住院患者中梅毒的感染率较高,对其检测梅毒抗体很有必要。
Objective To understand the prevalence and distribution of syphilis antibodies in hospitalized patients and to provide a scientific basis for the prevention and treatment of syphilis. Methods The specimens of the subjects were screened by ELISA. The positive samples were confirmed by TPPA. Results Of the 59 282 serum samples, 1834 were detected positive by TPPA, the positive rate was 3.09%. There were 865 males and 969 females. The positive rates of syphilis in different gender groups were not statistically different The highest infection rate was 5.39%. Compared with other groups, the difference was statistically significant (χ2 = 257.42, Р <0.01). The positive rate of syphilis in hospitalized patients was different in different years. From 2008 to 2013, the positive rate of syphilis in hospitalized patients The trend was decreasing year by year. Syphilis seropositive patients were not evenly distributed in all departments and distributed in all clinical departments. The medical system ranked first with an infection rate of 4.41%, followed by general surgery with an infection rate of 3.62%. Conclusions The current prevalence of syphilis in hospitalized patients is high, which is necessary for the detection of syphilis antibody.