纳洛酮为阿片受体拮抗剂,主要用于阿片类药物复合麻醉术后,拮抗该类药物所至的呼吸抑制,促使病人苏醒。用于阿片类药物过量,完全或部分逆转阿片类药物引起的呼吸抑制。解救急性乙醇中毒。本文综述该药在治疗休克,乙醇中毒,麻醉中的低血压,心绞痛,心肺复苏,治疗脑卒中等疾病中的应用并对其作用机理进行简述。 Naloxone is an opioid receptor antagonist, which is mainly used for the opioid compound anesthesia to antagonize the respiratory depression caused by such drugs and promote the patient to wake up. For opioid overdose, complete or partial reversal of opioid-induced respiratory depression. Rescue acute alcohol poisoning. This article reviews the application of the drug in the treatment of shock, alcoholism, hypotension in anesthesia, angina pectoris, cardiopulmonary resuscitation, stroke and other diseases and its mechanism of action.