目的:调查分析2013 ～2015年我院门诊药房抗骨质疏松类药物利用情况,为临床合理用药提供参考.方法:将2013 ～2015年我院门诊使用的骨质疏松药物分为五大类,分别统计各类别的销售金额及构成比.采用限定日剂量(DDD)法,对门诊使用的19种抗骨质疏松药物的用药频度(DDDs)、限定日费用(DDC)、药品金额与DDDs序号比(K)进行统计分析.结果:2013 ～2015年我院抗骨质疏松药物的销售金额呈先下降再上升的趋势,相比于2013年,2015年的销售金额增长了17.10％.3年中活性维生素D都是总金额占比最高的类别,而降钙素类药物的销售金额占比逐年增加.DDDs排名第一的药品始终为我院自产的氨基酸钙片.DDC值最高的为鲑鱼降钙素喷鼻剂(金尔力),最低的为碳酸钙D3片(Ⅱ)(朗迪).大多数药品的K值接近于1.结论:2013 ～ 2015年我院抗骨质疏松药物使用基本合理.","Objective:Analyze the application of anti-osteoporosis drags from 2013 to 2015 in the out patient department of our hospital,to provide reference to clinical application.Methods:Anti-osteoporosis were classified into five groups,according to their pharmacological effects.Then,sale amounts and the percentage of total sales were calculated by groups.Defined daily doses (DDDs),defined daily cost (DDC),and K values of 19 anti-osteoporosis drags applied in the out patient department were further detected.Results:Sale amounts of anti-osteoporosis drugs fluctuated in 2013 to 2015,but the sale amounts of 2015 increased 17.10％,compared with that of 2013.Activated vitamin D occupied the largest part of sale amounts in the observed three years,the proportion of calcitonin(CT) sale amounts increased year by year.The DDDs of our hospital-made preparation amino acid calcium was far exceeded other anti-osteoporosis drugs.The DDC of salcatonin nasal spray was the highest,while calcium carbonate and vitamin D3 tablets(Ⅱ)was the lowest.Most investigated drugs' K values were approaching 1,which reveals the synchronization of sale amounts and drug doses.Conclusion:Application of anti-osteoporosis drugs is rational in the out patient department of our hospital from 2013 to 2015.