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目的:回顾性分析宫颈上皮内瘤变(CIN)Ⅲ患者行高频电波刀宫颈电圈环切术(LEEP)治疗及全子宫切除术后的随诊情况,探讨LEEP治疗CINⅢ的效果及临床价值。方法:选择2004年3月~2009年3月58例CINⅢ患者,其中46例行LEEP治疗(LEEP组),12例行全子宫切除术(对照组)。两组经正规随诊后对其临床资料进行分析,了解LEEP的治疗效果。结果:随诊中,LEEP组TCT检查异常者4例(8.6%,4/46),对照组1例(8.3%,1/12),两组对比,差异无统计学意义(P=0.1)。结论:LEEP治疗CINⅢ患者是安全、有效的,但需长期随访。
OBJECTIVE: To retrospectively analyze the follow-up of cervical ring electrosurgical excision (LEEP) and total hysterectomy in patients with cervical intraepithelial neoplasia (CIN) Ⅲ and to evaluate the effect and clinical value of LEEP in the treatment of CIN Ⅲ . Methods: From March 2004 to March 2009, 58 patients with CIN Ⅲ were selected. Of them, 46 patients underwent LEEP treatment (LEEP group) and 12 patients underwent hysterectomy (control group). Two groups after formal follow-up analysis of their clinical data to understand the therapeutic effect of LEEP. Results: Four cases (8.6%, 4/46) had abnormal TCT in LEEP group and one case (8.3%, 1/12) in control group, there was no significant difference between the two groups (P = 0.1) . Conclusion: LEEP treatment of CIN Ⅲ patients is safe and effective, but need long-term follow-up.