目的探讨子宫纵隔-双宫颈-阴道纵隔的诊治经验。方法检索北京协和医院病案科1984年至今的电子病案数据库,调集相关病例系统复习,根据手术记录对畸形描述进行复核和甄别。10例子宫纵隔-双宫颈-阴道纵隔特异畸形病例通过门诊病历和电话完善随访。结果 10例均有不孕病史,完全分隔的双宫颈患者除1例行开腹子宫纵隔切除术外,均行腹腔镜检查+宫腔镜子宫纵隔切除术+阴道纵隔切除术。自然受孕并足月剖宫产3例,距前次手术间隔2~3.5年。结论在不孕症诊治中存在子宫纵隔-双宫颈-阴道纵隔这种较为复杂的生殖道发育畸形。治疗上双宫颈不需处理,子宫纵隔的切除首选宫腔镜。 Objective To investigate the diagnosis and treatment of uterine mediastinum - double cervix - vaginal mediastinum. Methods The medical records database of Peking Union Medical College Hospital from 1984 to the present was retrieved and the relevant cases were reviewed for systematic review. The deformity description was reviewed and screened according to the surgical records. 10 cases of uterine mediastinum - double cervix - vaginal mediastinal malformation cases were outpatient medical records and telephone follow-up. Results All 10 patients had a history of infertility. In addition to complete laparotomy of double cervix in 1 patient undergoing laparotomy, laparoscopy and hysteroscopic mediastinal excision plus vaginal mediastinum were performed. Natural pregnancy and full-term cesarean section in 3 cases, from the previous surgery interval of 2 to 3.5 years. Conclusion In the diagnosis and treatment of infertility, there is the more complicated reproductive tract deformity of uterine mediastinum - double cervix - vaginal mediastinum. Treatment of double cervix without treatment, hysterectomy preferred hysteroscopic mediastinal resection.