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冠状动脉粥样硬化是糖尿病患者常见并发症。然而有关糖尿病心肌缺血／再灌注损伤变化特点的报道不多且相互矛盾。有人指出糖尿病大鼠心肌缺血后心功能恢复较正常鼠慢［１］；有人报道糖尿病动物对缺血耐受性更高［２～４］；还有人认为糖尿病及正常动物对心肌缺血／再灌注损伤
Coronary atherosclerosis is a common complication in patients with diabetes. However, there are few and conflicting reports about the characteristics of myocardial ischemia / reperfusion injury in diabetic patients. It was pointed out that diabetic rats have a slower recovery of cardiac function than normal rats after myocardial ischemia [1]; it has been reported that diabetics are more resistant to ischemia [2 ~ 4]; others think that diabetes and normal animals have an effect on myocardial ischemia / Reperfusion injury