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PTEN基因是迄今为止发现的第一个具有双特异性磷酸酶活性的抑癌基因 ,该基因的突变失活与多种肿瘤的发生有密切的关系。PTEN基因突变失活在泌尿系统肿瘤发生、发展中起着重要的作用。
The PTEN gene is the first tumor suppressor gene with bispecific phosphatase activity discovered so far. Mutation inactivation of this gene is closely related to the occurrence of various tumors. Inactivation of PTEN gene mutation plays an important role in the development and progression of urinary tumor.