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目的:考察氯霉素注射液细菌内毒素检查法的可引性。方法:干扰试验和对比试验。结果:0.5mg·ml~(-1)的样品溶液无干扰作用,与热原检查法结果一致。结论:将氯毒素注射液稀释250倍或250倍以上可用灵敏度为0.5EU·ml~(-1)的鲎试剂作细菌内毒素检查。
Objective: To investigate the catabolism of bacterial endotoxin in chloramphenicol injection. Methods: Interference test and comparative test. Results: 0.5mg · ml -1 sample solution had no interference effect, which was consistent with pyrogen test. Conclusion: The chlorotoxin injection can be diluted 250 times or more than 250 times with the sensitivity of 0.5EU · ml -1 for the bacterial endotoxin test.