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肿瘤坏死因子相关凋亡配体(TNFrelatedapoptosisinducingligand,TRAIL)是肿瘤坏死因子(TNF)超家族成员。TRAIL与其受体结合后能选择性诱导肿瘤细胞凋亡,而对正常组织细胞没有明显的伤害。以TRAIL为靶点的肿瘤治疗方法受到众多学者的关注。
Tumor necrosis factor-related apoptosis ligand (TRAIL) is a member of the tumor necrosis factor (TNF) superfamily. TRAIL and its receptor can selectively induce tumor cell apoptosis without obvious damage to normal cells. Tumor therapy targeting TRAIL has attracted the attention of many scholars.