论文部分内容阅读
近年来有关同型半胱氨酸血浓度和动脉粥样硬化间关系的临床研究日渐增多,本研究目的是为了确定血浆同型半胱氨酸浓度和高同型半胱氨酸血症与颈动脉粥样硬化危险性间的相关性。 研究对来自Framingham心脏研究中心,总共1041名老年病人,男418例,女623例,年龄67～96岁。用颈动脉多普勒超声检查评价颅外颈动脉狭窄,据狭窄程度将其分为二类:狭窄0～24％和狭窄25～100％。采集病人非空腹血浆标本,用酶学法测定血浆总胆固醇和高密度脂蛋白胆固醇,用Araki和Sako法测定总同型半胱氨酸,微量鉴定法测定血浆叶酸,放免法侧定VitB_12浓度,酪氨酸脱羧酶法测
In recent years, the clinical research on the relationship between plasma homocysteine concentration and atherosclerosis clinical research increasing, the purpose of this study is to determine the plasma homocysteine concentration and hyperhomocysteinemia and carotid atherosclerosis Harm of the correlation between the risk. A total of 1041 elderly patients were enrolled from the Framingham Heart Institute. There were 418 males and 623 females aged 67-96 years. Carotid artery Doppler ultrasound examination of extracranial carotid artery stenosis, according to the degree of stenosis will be divided into two categories: stenosis 0 ~ 24% and stenosis 25 ~ 100%. Plasma samples were collected from patients with non-fasting plasma, total cholesterol and high density lipoprotein cholesterol were measured by enzymatic method, total homocysteine was determined by Araki and Sako method, plasma folate was determined by micro-identification method, and the concentration of VitB_12 Determination of acid decarboxylase