酮症酸中毒(DKA)是儿童胰岛素依赖型糖尿病(IDDM)常见的并发症。小剂量胰岛素(0.1U·kg~(-1)·h~(-1))静脉滴注治疗收到良好效果。但对血糖≥28mmol/L(500mg/dl、血pH<7.2,或神志恍惚者疗效差,疗程长,我们试图在开始治疗的头几个小时加大胰岛素剂量[(0.15～0.35U)·kg~(-1)·h~(-1)),使血糖平稳、迅速下降,并找出不同血糖水平用不同剂量胰岛素的规律,初见成效。 资料与方法 一、临床资料,1.12例IDDM患儿男5例,女7例。年龄5～14岁,平均10岁。2.12例IDDM发生20例次DKA,由血糖及血pH证实。发生DKA的原因分别为感染15例次,自动停药2例次,饮食 Ketoacidosis (DKA) is a common complication of childhood insulin-dependent diabetes mellitus (IDDM). Small doses of insulin (0.1U · kg ~ (-1) · h ~ (-1)) intravenous drip treatment received good results. However, we sought to increase the insulin dose [(0.15-0.35 U) kg for the first few hours of treatment starting at ≥28 mmol / L (500 mg / dl, pH <7.2 or delirium) ~ (-1) · h ~ (-1)), making the blood sugar stable and rapid decline, and find different blood sugar levels with different doses of insulin law, initial effect. Materials and Methods First, the clinical data, 1.12 cases of IDDM children 5 males and 7 females. Age 5 to 14 years old, average 10 years old. 2.12 cases of IDDM occurred in 20 cases of DKA, confirmed by blood glucose and blood pH. The causes of DKA were 15 cases of infection, automatic withdrawal of 2 cases, diet