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利用细胞外记录技术,在麻醉大鼠丘脑中央下核(Sin)及其邻近结构内,共记录到192个神经元。78%的神经元对皮肤伤害性刺激发生反应。其中,大多数(118)被兴奋,28个被抑制,4个对某些部位的刺激兴奋,而对另一些部位的刺激抑制。发现某些神经元有很长的后发放效应,另一些则在兴奋之后跟随着较长的抑制期,少数的反应仅在刺激给与和撤除的瞬间发生。感受野大且呈双侧分部。80%对机械刺激反应的神经元也对伤害性热刺激发生相同的反应。没有发现对非伤害性刺激反应的神经元。神经元的反应特性在Sm及其邻近结构之间没有任何差异。结果提示,Sin及其邻近结构可能参与机体的伤害性感受并与痛觉的情绪激动成分有关。
Using extracellular recording technique, a total of 192 neurons were recorded in the central thalamic nucleus (Sin) and its adjacent structures in anesthetized rats. 78% of the neurons respond to skin noxious stimuli. Among them, the majority (118) were excited, 28 were inhibited, 4 were stimulated to some parts of the excitement while others were stimulated to restrain. Some neurons were found to have a long post-release effect, others followed by a longer period of inhibition following excitement, and a few responses occurred only at the moment of stimulus delivery and removal. Feel wild and were bilateral division. Eighty percent of neurons responding to mechanical stimuli also respond identically to noxious thermal stimuli. No neurons responding to non-noxious stimuli were found. The response characteristics of neurons did not differ between Sm and its neighboring structures. The results suggest that Sin and its adjacent structures may participate in the nociception of the body and are related to the emotional components of pain.