支气管肺发育不良(bronchopulmonary dysplasia,BPD)是一种临床较为常见的慢性肺部疾病,在机械通气运用到临床之前还没有被人们所认识,1967年Northway和他的同事首次对本病进行了描述。目前公认的临床定义为生后最初两周需要至少三天的机械正压通气,合并呼吸困难症状,且在生后2 Bronchopulmonary dysplasia (BPD) is a relatively common clinical chronic lung disease that has not been recognized before mechanical ventilation is applied to the clinic. This is the first time that Northway and his colleagues described the disease in 1967 . The currently accepted clinical definition is mechanical positive pressure ventilation requiring at least three days in the first two weeks of life with symptoms of dyspnea, and 2