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目的了解余姚市食源性疾病中沙门菌菌型分布和耐药情况,为沙门菌临床治疗和防治提供科学依据。方法对哨点医院采集的腹泻患者样本进行增菌、分离、鉴定、血清分型和药敏试验。结果 2014年-2015年共收集860份食源性疾病患者标本,检出沙门菌108株,检出率为12.56%。共分属5个血清群24个血清型,其中鼠伤寒沙门菌占42.59%,是本地区近2年沙门菌感染的优势血清型。药敏试验发现,对青霉素类的耐药率较高,其中对氨苄西林的耐药率为44.44%,对哌拉西林的耐药率为39.81%。耐药株有68株,占62.96%,其中单一耐药2株,占1.85%,多重耐药有10株,占14.71%。结论余姚市沙门菌优势血清型以鼠伤寒沙门菌为主;部分菌株耐药性较明显,提示加强沙门菌耐药性监测的必要性。
Objective To understand the distribution and drug resistance of Salmonella in food-borne diseases in Yuyao, and provide a scientific basis for the clinical treatment and prevention of Salmonella. Methods The samples of diarrhea collected from sentinel hospital were enriched, isolated, identified, serotyped and drug susceptibility tested. Results A total of 860 samples of food-borne diseases were collected from 2014 to 2015. 108 strains of Salmonella were detected with a detection rate of 12.56%. There are 24 serotypes of 5 serogroups, of which 42.59% are Salmonella typhimurium, which is the predominant serotype of Salmonella infection in the region for nearly 2 years. Drug susceptibility test found that the resistance rate to penicillin was higher, among which the resistance rate to ampicillin was 44.44% and the resistance to piperacillin was 39.81%. There were 68 resistant strains (62.96%), of which 2 were single resistant, accounting for 1.85% and 10 were multi-resistant, accounting for 14.71%. Conclusion Salmonella typhimurium predominant serotypes are mainly Salmonella typhimurium in Yuyao City, and some strains are more drug-resistant, suggesting the necessity of monitoring Salmonella resistance.