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目的：了解氯化镉对肾上腺皮质细胞分泌功能、细胞［Ｃａ２＋］ｉ调控和能量代谢的毒作用，为深入了解金属内分泌毒性机制提供依据。方法：体外分离培养豚鼠肾上腺皮质细胞，采用Ｆｌｕｏ－３／ＡＭ和Ｆｕｒａ－ｒｅｄ／ＡＭ联合标记、以Ｆｌｕｏ－３／Ｆｕｒａ－ｒｅｄ比值表
OBJECTIVE: To understand the toxic effect of cadmium chloride on the secretion of adrenocortical cells, the regulation of [Ca2 +] i and the energy metabolism of cells, providing the basis for further understanding of the mechanism of metal endocrine toxicity. METHODS: Guinea pig adrenal cortical cells were isolated and cultured in vitro. Fluo-3 / Fura-red / AM and Fluo-3 / Fura-red ratio