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目的:比较研究托吡酯和盐酸氟桂利嗪在偏头痛治疗中的效果。方法:择取我院于2015年6月2017年6月期间收治的偏头痛患者118例,根据患者的个人意愿划分为A组和B组,每组各59例,A组患者口服盐酸氟桂利嗪,B组患者口服托吡酯,治疗12周后对比两组患者的疗效及不良反应。结果:B组患者的疗效优于A组,组间存在统计学差异,P<0.05;两组患者服药后的不良反应无统计学差异,P>0.05。结论:相较于盐酸氟桂利嗪,偏头痛患者服用托吡酯具有更好的临床疗效,且不良反应少,安全性较高,具有重要的临床意义,值得推广和应用。
OBJECTIVE: To compare the effects of topiramate and flunarizine hydrochloride in the treatment of migraine. Methods: A total of 118 migraineurs admitted to our hospital from June 2015 to June 2017 were divided into group A and group B (59 patients in each group) according to their individual wishes. Group A patients received oral fluorouracil In the group B, patients were given topiramate, and the curative effect and adverse reactions of the two groups were compared after 12 weeks of treatment. Results: The curative effect of group B was better than that of group A, with statistical difference between the two groups (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion: Compared with flunarizine hydrochloride, migraine patients taking topiramate has better clinical curative effect, less adverse reactions and higher safety, which is of important clinical significance and worthy of promotion and application.