表位,又称抗原决定簇,是指免疫应答中被特异的效应分子或T、B淋巴细胞识别的抗原分子的特定结构位点。B细胞表位是指抗原中可被B细胞抗原受体(BCR)或抗体特异性识别并相互结合的线性片段或空间构象型结构。B细胞表位的预测对免疫原性多肽和新型疫苗分子的设计都有很大的帮助,并 Epitopes, also known as antigenic determinants, refer to specific structural sites of antigen molecules recognized by specific effector molecules or T, B lymphocytes in an immune response. B cell epitopes refer to linear segments or steric conformational structures in an antigen that are specifically recognized by B cell antigen receptors (BCRs) or antibodies and bind to each other. Prediction of B-cell epitopes is of great help to the design of immunogenic polypeptides and novel vaccine molecules, and