An efficient route for synthesis of 2-alkylamino benzo [b] thieno [3,2-d]pyrimidin-4(3H)-one

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The carbodiimide 2, obtained from the aza-Wittig reactions of iminophosphorane 1 with alkyl isocyanates, reacted with primary amino to give 2-alkylamino benzo[b]thieno[3,2-d]pyrimidin-4(3H)-ones 4 and 5. The formation mechanism of the title compounds has been investigated.
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