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1987年1月至1993年9月我院分娩孕妇12716例,其中妊娠期肝内胆汁郁积症(ICP)443例,发生率3.48%。ICP 主要表现为皮肤瘙痒、黄痘及 SGPT 升高.443例中发生早产85例,发生率为19.2%。死胎13例,死产8例,新生儿早期死亡3例,围产儿病死率为54.2‰.新生儿 Apgar 评分≤7分者48例,占10.8%.新生儿平均体重3082g.本文认为,早期诊断,孕期加强监护,产时严密观察产程进展、胎心变化,羊水情况,积极处理产程是降低 ICP 并发症的有效措施.
From January 1987 to September 1993, 12,716 pregnant women were delivered in our hospital, of which 443 cases were intrahepatic cholestasis of pregnancy (ICP), the incidence rate was 3.48%. The main manifestations of ICP were skin itching, yellow smallpox and SGPT, 85 cases of premature delivery occurred in 443 cases, the incidence was 19.2%. 13 cases of stillbirth, 8 cases of stillbirth, 3 cases of early neonatal death, perinatal mortality was 54.2 ‰ .New infants Apgar score ≤ 7 points in 48 cases, accounting for 10.8% .The average weight of newborns 3082g.In this paper, early diagnosis Intensive care during pregnancy, during labor closely observe the progress of labor, fetal heart rate changes, amniotic fluid situation, and actively manage the labor process is to reduce ICP complications effective measures.