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目的分析骨髓细胞形态学检查对骨髓增生异常综合征的诊断价值。方法选取2013年11月-2016年11月于医院就诊及治疗的骨髓增生异常综合征患者100例作为观察组,并选取同时期于医院就诊及治疗的非克隆性疾病患者100例作为对照组,对比分析2组患者的外周血涂片的检查结果、粒细胞系相关指标、红细胞系相关指标、巨核细胞系相关指标。结果观察组患者的原粒细胞、幼粒细胞、幼红细胞、巨核细胞的比例均高于对照组,差异均有统计学的意义(P<0.05)。观察组患者的粒细胞系相关指标比例均高于对照组,差异有统计学意义(P<0.05)。观察组患者的红细胞系相关指标比例均高于对照组,差异有统计学意义(P<0.05)。观察组患者的多圆核、单圆核、畸形血小板、淋巴样小巨核的比例均高于对照组,差异均有统计学意义(P<0.05)。结论骨髓细胞形态学检查对于骨髓增生异常综合征患者的诊断具有重要价值。
Objective To analyze the diagnostic value of bone marrow cell morphology in the diagnosis of myelodysplastic syndromes. Methods 100 cases of myelodysplastic syndrome patients treated and treated in the hospital from November 2013 to November 2016 were selected as the observation group and 100 cases of non-clonal disease patients treated and treated in the hospital were selected as the control group, Comparative analysis of two groups of patients with peripheral blood smear test results, granulocyte-related indicators, red blood cell-related indicators, megakaryocyte-related indicators. Results The proportions of myeloblasts, myelocytes, erythroblasts and megakaryocytes in the observation group were significantly higher than those in the control group (P <0.05). The proportion of granulocyte-related indicators in the observation group was higher than that in the control group, the difference was statistically significant (P <0.05). The proportion of erythrocyte related indicators in the observation group was higher than that in the control group, the difference was statistically significant (P <0.05). The ratio of multicentric nucleus, mononuclear nucleus, deformity platelet and lymphoid megakaryocyte in the observation group was higher than that in the control group, with statistical significance (P <0.05). Conclusion The morphological examination of bone marrow cells is of great value in the diagnosis of patients with myelodysplastic syndromes.