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环吡酮胺是九十年代深受国际上推崇的一种新型广谱抗真菌药。与咪唑类(克霉唑、酮康唑、益康唑等)相比具有很强的穿透性,并且对皮肤组织无刺激,高效,安全,是美国21版药典唯一收载的抗真菌药。目前国内已有河南许昌制药厂独家生产的环吡酮胺软膏上市。1.药理作用:国外研究证明,环吡酮胺对皮肤真菌、二形真菌(Dimorphic fungi)有抑制作用。尤其对革兰氏阴性菌疗效显著。它作用于真菌的细胞膜,破坏细胞膜的完整性,使细胞内的钾离子和其它物质漏出,从而发挥
Ciclopirox olamine is a new type of broad-spectrum antifungal agent that is internationally respected in the nineties. Compared with the imidazoles (clotrimazole, ketoconazole, econazole, etc.) compared to a strong penetration, and the skin is not stimulating, efficient and safe, the United States Pharmacopoeia 21 version of the only antifungal . At present, Henan Hichang Pharmaceutical Factory has exclusive production of ciclopirox olamine market. Pharmacological effects: Foreign studies have shown that ciclopirox olamine inhibit dermatophytes, Dimorphic fungi (Dimorphic fungi). Especially for Gram-negative bacteria significant effect. It acts on the cell membrane of the fungus, destroying the integrity of the cell membrane, leaking potassium ions and other substances inside the cell, and thus play