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环境中具有雌激素和抗雄激素性质的内分泌干扰物可导致隐睾病,尿道下裂、睾丸肿瘤和精子密度降低。邻苯二甲酸和某些氯化烃(二恶英等)对雄性动物生育能力有很多不利影响。表现为精液量和精子数量减少,精子运动能力低下、形态异常,严重的会导致睾丸癌。其他化学物质如:双酚A和壬基苯酚,对动物生育能力的影响尚有争议。在人早期发育过程中,长期接触这类化学物质,可致成年后机体对激素的反应性发生改变。而成年后长期大剂量接触,可以导致生殖功能下降,主要包括精子质量下降和数量减少、先天性隐睾和尿道下裂发生率上升、不育症发生率上升等。
Endocrine disruptors with estrogenic and anti-androgenic properties in the environment can lead to cryptorchidism, hypospadias, testicular tumors, and sperm densities. Phthalates and some chlorinated hydrocarbons (dioxins, etc.) have a number of adverse effects on male fertility. The performance of the amount of semen and sperm to reduce the sperm motility is low, abnormal morphology, can lead to severe testicular cancer. Other chemical substances such as: bisphenol A and nonylphenol, the impact on animal fertility is still controversial. In the process of early human development, long-term exposure to such chemicals can cause the body’s reactivity to hormones after the body changes. And adult long-term high-dose exposure, can lead to decreased reproductive function, including the decline in sperm mass and reduce the number of congenital cryptorchidism and hypospadias incidence increased, the incidence of infertility and so on.