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目的:评价氨溴索治疗麻疹并发支气管肺炎患者的临床疗效。方法:将106例麻疹并发支气管肺炎患者随机分为对照组(53例)与治疗组(53例),对照组给予利巴韦林注射液、阿奇霉素或头孢菌素类、夜咳灵口服液抗病毒、抗感染与止咳化痰治疗;治疗组在对照组的治疗基础上,加用盐酸氨溴索注射液7.5mg加入5%葡萄糖注射液250mL中,bid,静脉滴注。观察患者症状与脉氧饱和度(SPO2)指标、影像学改善情况及平均住院日。结果:24h内SPO2得到改善,72h内症状得到缓解,平均住院日治疗组(5.08±1.05)d与对照组(5.85±1.44)d比较差异有统计学意义(P<0.05)。结论:盐酸氨溴索治疗麻疹并发支气管肺炎具有较好疗效。
Objective: To evaluate the clinical efficacy of ambroxol in patients with measles complicated with bronchial pneumonia. Methods: A total of 106 patients with measles complicated with bronchial pneumonia were randomly divided into control group (53 cases) and treatment group (53 cases). The control group was treated with ribavirin injection, azithromycin or cephalosporins, Virus, anti-infection and relieving cough and eliminating phlegm. The treatment group was treated with ambroxol hydrochloride injection (7.5mg) in 250mL of 5% dextrose injection on the basis of the treatment of the control group, bid, intravenously. Symptoms and symptoms of patients with oxygen saturation (SPO2) indicators, imaging improvements and the average length of stay. Results: The SPO2 was improved within 24 hours, and the symptoms were relieved within 72 hours. The mean length of hospital stay (5.08 ± 1.05) days was significantly different from that of the control group (5.85 ± 1.44 days) (P <0.05). Conclusion: Ambroxol hydrochloride in the treatment of measles complicated with bronchial pneumonia has good curative effect.